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Cyclizine works by blocking histamine and acetylcholine receptors in the brain, particularly in the area responsible for balance and motion detection. By doing this, it helps to prevent and reduce the sensation of nausea, dizziness, and vomiting. This makes it particularly useful for motion sickness, where conflicting signals between the inner ear and brain cause discomfort. It also helps manage nausea caused by inner ear disorders, general anaesthesia, or certain medical treatments.
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Cyclizine 50mg Tablets
Anti-sickness medicine
Yes
cyclizine hydrochloride
30 minutes
Cyclizine works by blocking histamine and acetylcholine receptors in the brain, particularly in the area responsible for balance and motion detection. By doing this, it helps to prevent and reduce the sensation of nausea, dizziness, and vomiting. This makes it particularly useful for motion sickness, where conflicting signals between the inner ear and brain cause discomfort. It also helps manage nausea caused by inner ear disorders, general anaesthesia, or certain medical treatments.
Skin rashes or itching, drowsiness, dizziness, headache, dried mouth and blurred vision, vomiting and constipation
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Cyclizine 50mg Tablets are used for nausea, vomiting and dizziness, including motion sickness, vertigo and inner ear disturbances. Cyclizine is an antihistamine with anti sickness properties, and it is a practical option for travel and for conditions that upset balance.
Cyclizine blocks histamine signalling in the vomiting centre of the brain and damps down messages arriving from the balance organs of the inner ear. Motion sickness and vertigo both arise when those balance signals conflict with what the eyes are reporting, so reducing the signal is what settles the nausea and the spinning sensation.
Swallow the tablets with water, following the directions on the pack. For travel, a dose taken before the journey begins works better than one taken once sickness has started, since it is easier to prevent nausea than to reverse it. Do not exceed the stated maximum in 24 hours.
It is for adults and children as stated on the pack. It is not suitable for anyone with a known sensitivity to cyclizine, and a pharmacist should check first if you have glaucoma, an enlarged prostate with difficulty passing urine, epilepsy, heart failure, or liver or kidney problems.
Drowsiness, dry mouth and blurred vision are common, so do not drive or operate machinery until you know how it affects you, and avoid alcohol. See a doctor for vertigo that is new, severe or accompanied by hearing loss, headache, weakness, double vision or difficulty speaking, and for vomiting that persists or stops you keeping fluids down. Our UK pharmacy team can answer questions about this product before you buy.
When should I take it for travel?
Before the journey starts, following the timing on the pack, rather than once you already feel sick.
Will it make me drowsy?
It can. Try the first dose when you do not need to drive.
Can I take it every day?
It is intended for short term use. Ask a pharmacist or GP if you need it regularly.
Always read the patient information leaflet supplied with the pack before use.
Medically reviewed and published
This page was medically reviewed by Dr Sohaib Imtiaz, Clinical Lead on
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